Google AI offshoot DeepMind announces a major breakthrough in solving what biologists call the “protein folding problem”—determining a protein’s 3D shape from its amino-acid sequence. Considered one of the field’s grand challenges due to myriad possible configurations, DeepMind’s AI system AlphaFold has demonstrated it can predict protein structures with high accuracy, vastly outperforming other more laborious, costly techniques. “It’s a game-changer,” says Andrei Lupas, an evolutionary biologist at the Max Planck Institute in Tübingen, Germany. “This will change medicine. It will change research. It will change bioengineering. It will change everything.”

A recent paper by amateur astronomer and YouTuber Alberto Caballero identifies a possible source of the Wow! signal, the curious cosmic radio blitz recorded in 1977 that expedited the search for extraterrestrial intelligence and puzzles experts to this day. Looking for “sun-like stars that might host an exoplanet capable of supporting intelligent life” in the signal’s celestial region, Caballero scanned ESA’s 1.3 billion star-strong Gaia database and found a potential match: “This candidate source, which is named 2MASS 19281982-2640123, therefore becomes an ideal target to conduct observations in the search for potentially habitable exoplanets.”

Algorithmic production has the potential to “free overworked and underpaid artists to pursue the aspects of their art that are most enjoyable, creative, or personally fulfilling.” Beyond the expected skepticism, Matthew Braga considers the nuances of automation, and draws on recent projects by writer Robin Sloan and musician Holly Herndon to illustrate how it might aid and augment beleaguered and spread-too-thin creatives.

Ahead of the sunsetting of Adobe Flash on Dec 31, the Internet Archive announces the preservation of Flash content—SWF files—through emulation. First introduced by Macromedia in 1996, the software was vital for dynamizing the early Web. “From roughly 2000 to 2005, Flash was the top of the heap for a generation of artists, animators, and small studios,” writes archivist Jason Scott, warning that a big part of Internet history is now “in true danger of sinking beneath the sea.” To run Flash files without the discontinued player, the non-profit digital library incorporated Ruffle, an in-development emulator, into the site. Thus far, more than 1,000 Flash classics have been ‘resurrected.’

The U.S. National Science Foundation (NSF) announces the decommission of the Arecibo Observatory after another snapped cable had caused further damages to its iconic radio dish. The decision was made when several independent engineering companies assessed that the telescope structure is “in danger of a catastrophic failure” and recommended controlled demolition “as soon as pragmatically possible.” Gutted by the news, scientists around the world flood social media with #WhatAreciboMeansToMe posts.